{"id":188,"date":"2018-11-02T12:51:00","date_gmt":"2018-11-02T10:51:00","guid":{"rendered":"https:\/\/biophysics.pmfst.unist.hr\/?p=188"},"modified":"2023-10-11T13:09:49","modified_gmt":"2023-10-11T11:09:49","slug":"javna-obrana-teme-doktorskog-rada-tomislava-roncevica","status":"publish","type":"post","link":"https:\/\/biophysics.pmfst.unist.hr\/en\/javna-obrana-teme-doktorskog-rada-tomislava-roncevica\/","title":{"rendered":"Javna obrana teme doktorskog rada Tomislava Ron\u010devi\u0107a"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>OBAVIJEST<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Javna obrana teme doktorskog rada studenta poslijediplomskog sveu\u010dili\u0161nog studija BIOFIZIKA<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>TOMISLAVA RON\u010cEVI\u0106A<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">odr\u017eat \u0107e se u ponedjeljak, <strong>12. 11. 2018.<\/strong> u <strong>14:00 sati<\/strong> na Prirodoslovno-matemati\u010dkom fakultetu u Splitu (<strong>dvorana B3-47<\/strong>), pred \u010dlanovima Stru\u010dnog povjerenstva:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>doc. dr. sc. Larisa Zorani\u0107, (Prirodoslovno-matemati\u010dki fakultet, Split), predsjednica<\/li>\n\n\n\n<li>doc. dr. sc. Ana Maravi\u0107, (Prirodoslovno-matemati\u010dki fakultet, Split), \u010dlan<\/li>\n\n\n\n<li>izv. prof. dr. sc. Vedrana \u010cike\u0161 \u010culi\u0107, (Medicinski fakultet, Split), \u010dlan<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Naslov:<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Ciljano sekvenciranje DNK i QSAR za identifikaciju antimikrobnih peptida iz \u017eaba (Anura) i re\/dizajn s ciljem pobolj\u0161anja aktivnosti<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Title:<br>Targeted DNA sequencing and QSAR for identification of anuran antimicrobial peptides and re\/design to improve activities<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract: <\/strong>Antimicrobial peptides (AMPs) are structurally diverse molecules naturally produced by all organisms, with direct antimicrobial activity against pathogens and often showing other immune-related properties. Anurans are a particularly rich source of these peptides, with 1923 different sequences reported in Database of Anuran Defense Peptides (DADP). We propose a novel approach for peptide identification by exploiting the highly conserved signal peptide region, RNAseq data&nbsp;available in Sequence Read Archive (SRA) database and selectively amplifying AMP-coding transcripts from small amounts of frog skin tissue. Additionally, novel peptides will be re\/designed with the help of molecular descriptors using software developed at Split University (e.g. Mutator) that links the biophysical properties of the peptides with their biological activity. This software has been trained on helical AMPs of anuran origin and may provide best results if natural peptides of anuran origin are used as input.<\/p>\n\n\n\n<div class=\"wp-block-file\"><a id=\"wp-block-file--media-b1f61b25-37b8-4c01-ae7c-c2f1ecfa6c22\" href=\"https:\/\/biophysics.pmfst.unist.hr\/wp-content\/uploads\/2023\/10\/Obavijest_o_javnoj_obrani_TEME_doktorskog_rada_TRoncevic.pdf\">Obavijest \u2013 javna obrana teme doktorskog rada Tomislava Ron\u010devi\u0107a<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>OBAVIJEST Javna obrana teme doktorskog rada studenta poslijediplomskog sveu\u010dili\u0161nog studija BIOFIZIKA TOMISLAVA RON\u010cEVI\u0106A odr\u017eat \u0107e se u ponedjeljak, 12. 11. 2018. u 14:00 sati na Prirodoslovno-matemati\u010dkom fakultetu u Splitu (dvorana B3-47), pred \u010dlanovima Stru\u010dnog povjerenstva: Naslov: Ciljano sekvenciranje DNK i QSAR za identifikaciju antimikrobnih peptida iz \u017eaba (Anura) i re\/dizajn s ciljem pobolj\u0161anja aktivnosti Title:Targeted<\/p>\n","protected":false},"author":1,"featured_media":690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[24,16],"tags":[],"class_list":["post-188","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-defense-of-topics-of-doctoral-theses","category-news-and-updates"],"acf":[],"_links":{"self":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/188","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/comments?post=188"}],"version-history":[{"count":3,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/188\/revisions"}],"predecessor-version":[{"id":688,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/188\/revisions\/688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/media\/690"}],"wp:attachment":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/media?parent=188"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/categories?post=188"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/tags?post=188"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}