{"id":409,"date":"2020-05-14T14:22:00","date_gmt":"2020-05-14T12:22:00","guid":{"rendered":"https:\/\/biophysics.pmfst.unist.hr\/?p=409"},"modified":"2023-10-11T13:07:42","modified_gmt":"2023-10-11T11:07:42","slug":"javna-obrana-teme-doktorskog-rada-matee-kanunnikau","status":"publish","type":"post","link":"https:\/\/biophysics.pmfst.unist.hr\/en\/javna-obrana-teme-doktorskog-rada-matee-kanunnikau\/","title":{"rendered":"Javna obrana teme doktorskog rada Matee Kanunnikau"},"content":{"rendered":"\n

OBAVIJEST<\/strong><\/p>\n\n\n\n

Javna online<\/em> obrana teme<\/strong> doktorskog rada studentice poslijediplomskog sveu\u010dili\u0161nog studija BIOFIZIKA<\/p>\n\n\n\n

MATEE KANUNNIKAU<\/strong><\/h2>\n\n\n\n

odr\u017eat \u0107e se u \u010detvrtak, 21. svibnja 2020. <\/strong>u 14.00 sati<\/strong>, pred \u010dlanovima Stru\u010dnog povjerenstva:<\/p>\n\n\n\n

    \n
  1. prof. dr. sc. Katarina Vukojevi\u0107, Medicinski fakultet Sveu\u010dili\u0161ta u Splitu, predsjednica<\/li>\n\n\n\n
  2. prof. dr. sc. Irena Drmi\u0107 Hofman, Medicinski fakultet Sveu\u010dili\u0161ta u Splitu, \u010dlanica<\/li>\n\n\n\n
  3. prof. dr. sc. Biljana Balen, Prirodoslovno-matemati\u010dki fakultet Sveu\u010dili\u0161ta u Zagrebu, \u010dlanica.<\/li>\n<\/ol>\n\n\n\n

    Mentorica:<\/strong> dr. sc. Anita Kri\u0161ko (Mediteranski institut za istra\u017eivanje \u017eivota, Split).<\/p>\n\n\n\n

    Naslov:<\/strong><\/p>\n\n\n\n

    Modifikacija statusa proteostaze: uloga komunikacije izme\u0111u stani\u010dnih organel<\/strong><\/h2>\n\n\n\n

    <\/p>\n\n\n\n

    Sa\u017eetak:<\/strong><\/p>\n\n\n\n

    Uravnote\u017eena proteinska homeostaza (proteostaza) je klju\u010dna za stani\u010dnu funkciju i odr\u017eivost organizma. Ona je djelomi\u010dno postignuta mre\u017eom proteinskih kofaktora pod nazivom \u2013 molekularni \u0161aperoni. Nemogu\u0107nost o\u010duvanja proteostaze mo\u017ee rezultirati te\u0161kim o\u0161te\u0107enjima koji mogu dovesti do stani\u010dne smrti. Gubitak proteinske homeostaze se smatra jednim od znakova starenja; broj o\u0161te\u0107enih i nepravilno nabranih proteina u stanici raste, dok proteosomalna razgradnja drasti\u010dno opada. Unato\u010d spoznaji da su starenje i disbalans proteostaze jako usko povezani, istra\u017eivanje koje se bavi ubla\u017eavanjem opadanja kontrole kvalitete proteina uslijed starenja zna\u010dajno kaska. Mi smo zainteresirani prou\u010diti posljedice koje promjene u proteostazi potpomognutoj \u0161aperonima imaju na cjelokupno stanje stanice. Ove promjene bi bile uzrokovane pobolj\u0161anjem ili propadanjem proteinske homeostaze. Tako\u0111er, htjeli bismo istra\u017eiti posljedice promjena u proteostazi lokaliziranim u stani\u010dnim odjeljcima.<\/p>\n\n\n\n

    Title:
    Modifying the proteostasis status: the role of cross-organelle communication<\/strong><\/p>\n\n\n\n

    Abstract:<\/h3>\n\n\n\n

    Balanced protein homeostasis (proteostasis) is essential for cellular function and the viability of the organism. This is, in part, achieved by a network of protein folding modulators, known as molecular chaperones. Failure to maintain proteostasis may result in severe damage that, in turn may lead to many diseases, and even cellular death. Loss of proteostasis is considered to be one of the hallmarks of aging, as the number of misfolded and aberrant proteins is increased, while the proteosomal degradation is drastically reduced. Despite knowing that aging and proteostasis imbalance is very closely related, the research on mitigating the age-associated decline in protein quality control is lagging behind. What we are interested in is to investigate the cell-wide repercussions following a change in chaperone-assisted proteostasis, either by its improvement or deterioration, as well as to examine the communication between affected cellular compartments with the rest of the cell.<\/p>\n\n\n\n

    Pozivaju se svi zainteresirani da prisustvuju online obrani putem Jitsi Meet sustava za koji je potrebno imati instalirani web preglednik Chrome ili Firefox.<\/p>\n\n\n\n

    Javnoj obrani teme pristupa se putem linka<\/p>\n\n\n\n

    https:\/\/meet.jit.si\/ObranaTemeDoktorskogRada_KanunnikauMatea<\/a><\/p>\n\n\n\n

    \"upute<\/figure>\n\n\n\n

    ili na mre\u017enoj stranici https:\/\/meet.jit.si<\/a> upisati naziv sastanka: ObranaTemeDoktorskogRada_KanunnikauMatea<\/strong><\/p>\n\n\n\n

    \"upute<\/figure>\n\n\n\n

    Priklju\u010denje javnoj obrani bit \u0107e mogu\u0107e od 13.30 h (21. svibnja 2020.).<\/p>\n","protected":false},"excerpt":{"rendered":"

    OBAVIJEST Javna online obrana teme doktorskog rada studentice poslijediplomskog sveu\u010dili\u0161nog studija BIOFIZIKA MATEE KANUNNIKAU odr\u017eat \u0107e se u \u010detvrtak, 21. svibnja 2020. u 14.00 sati, pred \u010dlanovima Stru\u010dnog povjerenstva: Mentorica: dr. sc. Anita Kri\u0161ko (Mediteranski institut za istra\u017eivanje \u017eivota, Split). Naslov: Modifikacija statusa proteostaze: uloga komunikacije izme\u0111u stani\u010dnih organel Sa\u017eetak: Uravnote\u017eena proteinska homeostaza (proteostaza) je<\/p>\n","protected":false},"author":1,"featured_media":690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[24,16],"tags":[],"class_list":["post-409","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-defense-of-topics-of-doctoral-theses","category-news-and-updates"],"acf":[],"_links":{"self":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/409","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/comments?post=409"}],"version-history":[{"count":4,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/409\/revisions"}],"predecessor-version":[{"id":682,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/posts\/409\/revisions\/682"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/media\/690"}],"wp:attachment":[{"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/media?parent=409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/categories?post=409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biophysics.pmfst.unist.hr\/en\/wp-json\/wp\/v2\/tags?post=409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}